Description
Scope
- Oxandrolone is widely used in medicine for children and women. In children, it perfectly restores the skin (after burns). In addition, it can be safely given to young athletes to increase their strength performance. This drug will not interfere with the hormonal system of the body. And will not cause any complications in the future.
- In strength sports, oxandrolone is often used between the main courses of anabolics. As I said above, it is a good anti-catabolic and does not suppress the production of your own testosterone. All this allows you to keep the muscle mass gained during the main course and at the same time restore your own hormonal background. That is, it allows the body to rest from the side effects of other anabolics, and in the meantime preserve muscles.
- In combination with stanozolol, oxandrolone is used to increase muscle strength without increasing body mass. This is especially true for those who don’t want to go beyond their weight class before competition.
- Its property of not increasing body mass and protecting muscles from breakdown is very useful in drying. That’s why it is often used when you want to make the body as relief as possible, but preserve muscles.
- Oxandrolone is also suitable for those who want to try steroids for the first time. If your body is not yet “accustomed” to anabolics, then even from small doses of oxandrolone you will feel an increase in strength performance.
Biological effect
Among other drugs of the steroid group, Anavar stands out due to its low androgynous effect. Its active component does not have the ability to aromatise – it is not converted into estrogens; liver toxicity is moderate, anabolic activity is 400% of testosterone. At daily doses of less than 20 mg it does not affect the secretion of this hormone, not inhibiting the hypothalamic-pituitary-testicular axis, after a three-month course it suppresses its production by 67-70%.
During clinical trials in patients with burns of more than 40% of the body surface area, improvement of tissue composition and acceleration of their regeneration were recorded when taking the drug. The drug was originally intended for:
treatment of disorders accompanied by loss of muscle mass;
complex HIV/AIDS therapy;
treatment of osteoporosis.
Due to its high popularity among athletes-culturists and the spread of cases of abuse in the sports environment, all dosage forms of the drug, its salts, isomers, esters were categorised as controlled substances in the USA, considered as a means of doping. The drug belongs to orphan drugs (means used for the treatment of rare diseases), shows high efficacy in the treatment of:
- alcoholic hepatitis;
- progressive muscular dystrophy;
- protein metabolism disorders against the background of trauma, burns, radiation therapy;
- Turner’s syndrome;
- weight loss in HIV-infected patients;
- hereditary Quincke’s oedema;
- anaemia;
- protein catabolism after prolonged corticosteroid therapy;
- osteochondrosis;
- osteoporosis.
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